B-Cell Linker anticorps (Middle Region)
Aperçu rapide pour B-Cell Linker anticorps (Middle Region) (ABIN2782531)
Antigène
Voir toutes B-Cell Linker (BLNK) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- QYALGRKKNG EEYFGSVAEI IRNHQHSPLV LIDSQNNTKD STRLKYAVKV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against BLNK. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human BLNK
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 456 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- B-Cell Linker (BLNK)
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Autre désignation
- BLNK
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Sujet
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This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological function
Alias Symbols: BASH, BLNK-s, Ly57, MGC111051, SLP-65, SLP65, bca, AGM4, LY57, BLNK-S
Protein Interaction Partner: ERBB2, BTK, GRAP2, SYK, PLCG1, CBL, AIFM1, NCK2, TLN1, MAP2K4, PPP2R2C, PLCG2, MYBPC3, LYN, HSPA4, GRB2, CD79A, CAPZB, CAPZA2, CAPZA1, CLEC17A, WDR81, DOK3, SH3KBP1, CD2AP, HSPH1, VAV3, CMTM3, CBLB, CRKL, MAP4K1, LCP2, NCK1, ITK, PTPN6, VAV1, CD72,
Protein Size: 456 -
Poids moléculaire
- 50 kDa
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ID gène
- 29760
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NCBI Accession
- NM_013314, NP_037446
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UniProt
- Q8WV28
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Pathways
- BCR Signaling
Antigène
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